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Contact us at (781) 937-3344 for further information! Choosing the right formulation is an important decision. Not only do we need to think about palatability and patient compliance, but we also need to consider bioavailability, efficacy, and safety. What we strive to achieve is an appropriate level of compromise between these elements. Many factors play into what the ultimate decision might be. At Pallimed Solutions, we use an extensive database of over 2,400 formulations that have all been peer reviewed. This means we do not compromise on your safety. At Pallimed, we can prepare medications in the following dosage forms: Capsules: Capsules are the best option when a patient needs a specially titrated dose, is allergic to the commercial fillers such as lactors, or when more than one medication needs to be combined together to maximize compliance. Due to the oral administration and the large amount of data supporting this dosage form, capsules are a great first line option. The powdered drug is enclosed in a non-flavored, hard gelatinous shell. Capsules are easy to swallow and mask bitter tastes. We can also combine several medications so the patient only has to take one capsule. Suppositories: Medication is imbedded in either a fatty acid base or PEG. This formulation is ideal for patients with no oral access, difficulty swallowing, or for nausea and vomitting. Rectal dosage formulations are a great way to administer medications when patients are unable to swallow, have limited gastrointestinal function, gastrophoresis, or during end-of-life stages when oral administration is very difficult. Rapid Dissolve Tablets: Pallimed Solutions specializes in Rapid Dissolve Tablet Therapy (RDT). This is the preferred method of administration when a patient still has normal gastrointestinal function but is unable to swallow. RDTs allow medication to be administered orally which allows us to predict safety and efficacy. Concentrate: Given by dropped onto the patient's tongue for ingestion. Medications can be given in smaller volumes than what traditional drug forms can administer. Liquid: Given via oral syringe or added to food for ingestion. This versatile method lets caregivers squirt a great tasting liquid into the mouth, or add to a favorite food.Emulsions: The drug is mixed in both the squeous or oil phase and remains evenly dispersed throughout the preparation. Bitter medications can be made more palatable. The absorption of some drugs can be increased when incorporated into an oil phase. Ointments & Transdermal Drug Delivery Systems (TDDS): Ointments and TDDSs are rubbed into the affected areas of the patient's skin. The medication is mixed with a topical gel that promotes absorption of the drug through the skin. Gels are a preferred route of administration for patients who cannot swallow and when the rectal route of administration is not an option. Although there are several case reports and anecdotal evidence supporting the efficacy of topical drug delivery, we recommend this as a last resort because of the lack of scientific data supporting the safety and efficacy of this route of administration. Lollipops: Pallimed prepares many medications in the form of a lollipop. The applications are endless, but lollipops are a good option when a patient has oral sores and we want to apply a topical anesthetic without swallowing the medication too quickly as one would with mouthwash or a buccal tablet. Otics: The drug is mixed wtih an aqueous or oil base. Medications are administered directly to the ear, often increasing effectiveness and decreasing cost and potential for toxicity. Gummie Chew: The medication is mixed in a chewable treat base and flavored to the patient's preference. The base can also be used for a slow-release "sucker." This form of medication is great for mouth sores, xerostoma, and other oral con ditions. PED Troche: The medication is included in a sem-soft preparation that is less chewy than a Gummie Chew. This is available in multiple sizes in a solid form. Opthalmics: The drug is mixed with an aqueous or oil base using USP guidelines for sterile preparation. Sterile medications are administered directly to the eye, increasing efficacy and lowering cost and potential for toxicity. All Compounded preparations require a prescription from your doctor.
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